Episode # 219 • 22 Apr 2025
New Frontiers in Pediatric Hearing Loss: Implants, Gene Therapy & CMV
Are new solutions for pediatric hearing loss finally within earshot? In this episode of the Back Table ENT Podcast, we talk with Dr. Daniela Carvalho, pediatric otolaryngologist and director of the Cochlear Implant Program at Rady Children's Hospital in San Diego.
Timestamps
00:00 - Introduction
01:54 - Understanding Congenital Hearing Loss and Screening
05:41 - Challenges with Older Children and Hearing Loss
08:48 - Cochlear Implants: Indications and Advances
15:59 - Exploring Gene Therapy for Hearing Loss
23:54 - Challenges and Considerations in Gene Therapy
25:23 - Counseling Families on Hearing Loss
27:04 - Future of Genetic Therapy and Cochlear Implants
32:46 - Addressing Congenital CMV
40:59 - Final Thoughts and Future Research
Resources
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More about this episode
Dr. Carvalho discusses the latest advancements and practices in the field of pediatric hearing loss, including newer indications for cochlear implants and innovative gene therapies. They delve into the genetic causes of congenital hearing loss, current screening practices, and various gene therapies being tested for hearing deficiencies, such as those involving the OTOF gene and its application through viral vectors. The conversation also touches on the potential for future treatments, including completely implantable cochlear devices and the role of vaccines in preventing CMV-related hearing loss.
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