BackTable / ENT / Podcast / Episode #235

Biologics for Chronic Rhinosinusitis with Nasal Polyps

with Dr. Reena Mehta

How do we integrate biologics into the existing stepwise treatment model for chronic rhinosinusitis with nasal polyps (CRSwNP)? In this episode, Dr. Reena Mehta, an allergist from Uptown Allergy and Asthma in New Orleans, discusses the use of biologics for treating chronic rhinosinusitis with nasal polyps.

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Biologics for Chronic Rhinosinusitis with Nasal Polyps with Dr. Reena Mehta on the BackTable ENT Podcast

Ep 235 Biologics for Chronic Rhinosinusitis with Nasal Polyps with Dr. Reena Mehta

00:00 / 01:04

BackTable, LLC (Producer). (2025, August 5). Ep. 235 – Biologics for Chronic Rhinosinusitis with Nasal Polyps [Audio podcast]. Retrieved from https://www.backtable.com

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Podcast Contributors

Dr. Ashley Agan

Dr. Ashley Agan is an otolaryngologist in Dallas, TX.

Dr. Reena Mehta

Dr. Reena Mehta is a private practice Allergist and adjuct professor at Tulane University Schoole of Medicine in New Orleans, Louisiana.

Dr. Gopi Shah

Dr. Gopi Shah is a pediatric otolaryngologist and the co-host of BackTable ENT.

Synopsis

Dr. Mehta elaborates on the common presentations of patients, the role of biologics such as dupilumab and tezepelumab, and the nuances of patient management post-sinus surgery. Dr. Mehta also covers the workup process, the significance of patient comorbidities like asthma and allergies, and the future perspectives on biologic treatments. Practical aspects of biologic therapy, including insurance hurdles, patient compliance, and the effectiveness of various biologics are thoroughly examined.

Timestamps

00:00 - Introduction
02:27 - Understanding Chronic Rhinosinusitis with Nasal Polyps & Presentation
05:22 - Workup and Management of Nasal Polyps
07:31 - Treatment Options: Steroids and Biologics
15:28 - Tezepelumab: A New Tool in the Toolkit
25:03 - Side Effects and Safety of Biologics
28:59 - Insurance and Approval Challenges
36:14 - Long-Term Safety and Efficacy
38:47 - Pediatric Considerations and Future Directions
41:37 - Collaboration Between ENT and Allergy Specialists
45:07 - Conclusion and Final Thoughts

Resources

Dr. Reena Mehta
https://uptownallergyasthma.com/allergist-dr-reena-mehta/

The Materials available on BackTable are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.

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