Episode # 87 • 11 Nov 2025
Advanced Techniques in Orthopedic Oncology: Bone Ablation for Skeletal Metastases
“We learn traditionally that bone metastasis is terminal.” 一 Or is it? In this episode of the BackTable MSK podcast, host Dr. Jacob Fleming welcomes Dr. Francis Lee, a leading figure in orthopedic oncology, to discuss advancements in treating skeletal metastasis. Dr. Lee, the Wayne O. Southwick Professor from Yale and President-elect of the Musculoskeletal Tumor Society, shares his innovative AORIF (Ablation, Osteoplasty, Reinforcement and Internal Fixation) technique, which emphasizes collaboration between orthopedic oncologists and interventional radiologists.
This podcast is supported by an educational grant from Medtronic.
Timestamps
00:00 - Introduction
01:39 - Crash Course: Orthopedic Oncology 101
13:24 - The Important Role of Biomechanics
20:10 - Dr Lee’s Training and Interdisciplinary Collaboration
28:13 - Intraoperative Imaging and Techniques in AORIF
40:15 - Cannulated Screws for Access and Fixation
42:24 - Case Study: Sacral Insufficiency Fracture and Cement Injection
44:17 - Understanding Cement Properties and Application
46:45 - Case Study Series: Approach to Reconstruction
57:58 - Decision Making in Complex Procedures
01:08:40 - The Power of Bone Regeneration
01:12:31 - Final Thoughts
Resources
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More about this episode
The conversation covers the complexities of bone metastasis, the biomechanics of skeletal ablation, and the importance of understanding bone-cancer interactions. Dr. Lee also shares insights from his translational research on cancer and bone dynamics, and emphasizes the need for continued interdisciplinary collaboration to drive forward minimally invasive treatments.
Medtronic was not involved in the creation or delivery of any program content and does not control whether the materials conform to an FDA approved or cleared indication.
The Materials available on BackTable are provided for informational and educational purposes only and are not a substitute for the independent professional judgment of a qualified healthcare professional in diagnosing or treating patients. Any opinions, statements, or views expressed are those of the individual contributors and do not necessarily reflect those of the publisher, platform, or any affiliated organization.