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BackTable / Tumor Board / Podcast / Episode #30
NMIBC Tumor Board: Nuances in Management
with Dr. Mark Tyson and Dr. Sarah Psutka
When standard therapy fails, it does not have to be the end of the road for high-risk bladder cancer patients. Modern treatments, biomarkers, and clinical studies have opened up new avenues for treating recurrent non-muscle invasive bladder cancer (NMIBC). The penultimate episode of the 2025 NMIBC Creator Weekend™ series features urologic oncologists Dr. Vignesh Packiam, Dr. Mark Tyson, and Dr. Sarah Psutka discussing how they navigate complex bladder cancer scenarios.
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BackTable, LLC (Producer). (2025, October 7). Ep. 30 – NMIBC Tumor Board: Nuances in Management [Audio podcast]. Retrieved from https://www.backtable.com
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Podcast Contributors
Synopsis
The doctors share treatment strategies, staging processes, and post-therapy patient management techniques. They address recurrent disease, approaches to different stages of cancer, the role of biomarkers in determining treatment paths, and considerations for both high-risk and intermediate-risk patients. Additionally, the episode touches on new treatments, clinical trials, and patient quality of life post-treatment.
Timestamps
00:00 - Introduction
02:08 - Case Study: Initial Patient Assessment
04:59 - Surgical Considerations and Techniques
10:22 - Managing Bladder Cancer Recurrence
11:15 - Treatment Options and Clinical Trials
15:12 - Advanced Treatment Strategies
28:14 - Closing Remarks and Credits
Resources
VISTA Trial https://abstracts.mirrorsmed.org/abstracts/vista-phase-3-trial-vicinium-epcam-targeted-pseudomonas-exotoxin-bcg-unresponsive-non
BRIDGE Trial
https://pmc.ncbi.nlm.nih.gov/articles/PMC10515442/
CORE-008 Trial
https://www.sciencedirect.com/science/article/abs/pii/S1078143924010147
GAIN Trial
https://pmc.ncbi.nlm.nih.gov/articles/PMC10176900/
The Materials available on BackTable are provided for informational and educational purposes only and are not a substitute for the independent professional judgment of a qualified healthcare professional in diagnosing or treating patients. Any opinions, statements, or views expressed are those of the individual contributors and do not necessarily reflect those of the publisher, platform, or any affiliated organization.
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