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BackTable / Cardiology / Podcast / Episode #2
Cardiogenic Shock Management: Latest Strategies & Innovations
with Dr. Amir Kaki, Dr. Sameh Sayfo
In 2024, the DanGer Shock trial changed cardiogenic shock guidelines and affected practice patterns internationally. This episode of the BackTable Cardiology Podcast explores tips, tricks, and best practices in utilizing Impella, ECMO, and national initiatives to most effectively treat patients with cardiogenic shock. Host Dr. Sameh Sayfo interviews Dr. Amir Kaki, a noted interventional cardiologist and Director of Mechanical Circulatory Support and Complex PCI at Henry Ford St. John Hospital in Detroit.
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BackTable, LLC (Producer). (2025, September 16). Ep. 2 – Cardiogenic Shock Management: Latest Strategies & Innovations [Audio podcast]. Retrieved from https://www.backtable.com
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Podcast Contributors
Synopsis
The discussion centers on the advances in mechanical circulatory support devices like Impella and ECMO, their history, usage criteria, and impact on patient outcomes. Dr. Kaki details the landmark Detroit Cardiogenic Shock Initiative, the challenges surrounding ECMO use, and the critical implementation of the recent DanGer-SHOCK Trial in clinical practice. After outlining the history of interventions for cardiogenic shock and the significance of recent trials within the field, he emphasizes the necessity for contemporary cardiologists to be skilled in endovascular techniques.
Timestamps
00:00 - Introduction
02:12 - National Cardiogenic Shock Initiative
06:23 - Shock 2 Trial
07:48 - ECLS-SHOCK Trial and ECMO
15:05 - DanGer Trial
22:56 - Parameters for Impella RP vs Impella CP Use in Cardiogenic Shock
29:39 - Impella Considerations: Placement, Limb Ischemia, Removal
37:56 - Modern Cardiogenic Shock: Overview and Resources
40:16 - Conclusion
Resources
The National Cardiogenic Shock Initiative:
https://www.ahajournals.org/doi/10.1161/JAHA.123.031401
DanGer Shock Trial:
https://www.acc.org/Latest-in-Cardiology/Clinical-Trials/2024/04/05/04/44/danger-shock
Large-Bore Access Site Management
https://assets.bmctoday.net/citoday/pdfs/cit0719_SF2_Kaki.pdf
Short-Term Mechanical Circulatory Support for Cardiogenic Shock
https://scai.org/publications/ebooks/short-term-mechanical-circulatory-support-cardiogenic-shock
Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock
https://www.nejm.org/doi/full/10.1056/NEJMoa1208410
Extracorporeal Life Support in Infarct-Related Cardiogenic Shock
https://www.nejm.org/doi/full/10.1056/NEJMoa2307227
Dr. Amir Kaki, MD
https://www.heartteam.com/provider/amir-kaki-md
https://scai.org/about-us/scai-staff-listing/amir-kaki-md-fscai
Dr. Sameh Sayfo
https://www.bswhealth.com/physician/sameh-sayfo
The Materials available on BackTable are provided for informational and educational purposes only and are not a substitute for the independent professional judgment of a qualified healthcare professional in diagnosing or treating patients. Any opinions, statements, or views expressed are those of the individual contributors and do not necessarily reflect those of the publisher, platform, or any affiliated organization.
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