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Dr. Ravindra Uppaluri on the BackTable ENT Podcast

Dr. Ravindra Uppaluri

Head and Neck Surgeon

2 Podcasts on BackTable

Dr. Ravindra Uppaluri is the Director of Head and Neck Surgical Oncology at the Brigham and Women's Hospital in Boston, Massachusetts.

Learn from the experiences and expertise of Dr. Ravindra Uppaluri and other leading voices in your specialty on the BackTable app.

Understanding Keynote-689: Immunotherapy for Head & Neck Cancer
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Episode # 32  •  28 Oct 2025

Understanding Keynote-689: Immunotherapy for Head & Neck Cancer

While the standard for adjuvant head and neck cancer treatment hasn't changed since 2004, a new trial using perioperative pembrolizumab is forcing clinicians to rethink their entire workflow, starting with diagnosis. In this episode of the BackTable Podcast, head and neck surgical oncologist Dr. Adam Luginbuhl is joined by colleagues Dr. Dylan Roden and Dr. Ravindra Uppaluri to discuss the implementation and implications of the Keynote-689 trial, which introduced neoadjuvant and adjuvant immunotherapy for locally advanced head and neck cancer.

More from Dr. Ravindra Uppaluri

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HNC: T4N2bM0 High Volume Primary Locally Advanced Head & Neck Squamous Cell Carcinoma

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About

Dr. Ravindra Uppaluri, MD/PhD is Director of Head and Neck Surgical Oncology at the Brigham and Women’s Hospital and Dana-Farber Cancer Institute. Dr. Uppaluri completed his MD/PhD at the University of Minnesota and subsequently his Otolaryngology residency at Barnes-Jewish Hospital and the Washington University School of Medicine, St. Louis, MO where he remained as a faculty member for the last 16 years. His clinical expertise is in multidisciplinary management of head and neck cancers, including minimally invasive transoral laser microsurgery, and endoscopic and open approaches to anterior skull base pathologies. Dr. Uppaluri has been the PI of clinical trials integrating small molecule and immunotherapeutics in the surgical management of head and neck cancers. He also leads an NIH funded laboratory focused on basic and translational approaches to head and neck cancers.

Visit Dana-Farber Cancer Institute to learn more about Dr. Ravindra Uppaluri.

The Materials available on BackTable are provided for informational and educational purposes only and are not a substitute for the independent professional judgment of a qualified healthcare professional in diagnosing or treating patients. Any opinions, statements, or views expressed are those of the individual contributors and do not necessarily reflect those of the publisher, platform, or any affiliated organization.

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