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BackTable / ENT / Podcast / Episode #212

Allergy Immunotherapy & The Microbiome

with Dr. Jennifer Villwock

Could the key to more effective allergy therapies lie in the nasal microbiome? In this episode of BackTable ENT, Dr. Jennifer Villwock from Kansas University Medical Center discusses the intricacies of treating allergies and sinus issues with hosts Dr. Ashley Agan and Dr. Gopi Shah.

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Allergy Immunotherapy & The Microbiome with Dr. Jennifer Villwock on the BackTable ENT Podcast
Ep 212 Allergy Immunotherapy & The Microbiome with Dr. Jennifer Villwock
00:00 / 01:04

BackTable, LLC (Producer). (2025, February 25). Ep. 212 – Allergy Immunotherapy & The Microbiome [Audio podcast]. Retrieved from https://www.backtable.com

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Podcast Contributors

Dr. Ashley Agan on the BackTable ENT Podcast

Dr. Ashley Agan is an otolaryngologist in Dallas, TX.

Dr. Gopi Shah on the BackTable ENT Podcast

Dr. Gopi Shah is a pediatric otolaryngologist and the co-host of BackTable ENT.

Dr. Jennifer Villwock on the BackTable ENT Podcast

Dr. Jennifer Villwock is an associate professor of otolaryngology at University of Kansas Medical Center in Kansas City, Kansas.

Synopsis

Dr. Villwock begins by highlighting the importance of personalized medicine and the role of the microbiome in immunotherapy. Topics include topical and oral probiotics, the nasal microbiome, intralymphatic immunotherapy, and the significance of accurate allergy testing. Dr. Villwock also shares insights on sublingual and subcutaneous immunotherapy, the future of allergy treatments, and the impact of environmental factors on sinus health.

Timestamps

00:00 - Introduction
01:53 - Understanding the Sinus Microbiome
04:34 - The Role of the Microbiome in Health
09:31 - Challenges in Microbiome Research
23:21 - Clinical Decision-Making in Antibiotic Use
25:07 - Exploring Probiotics & Dietary Factors for Sinus Health
30:12 - Immunotherapy and Microbiome
35:47 - Allergy Testing Methods
41:40 - Future Directions in Immunotherapy
44:18 - Conclusion and Final Thoughts

Resources

AAOA 2025 Explorers Course in Allergy and Immunology, Vail, CO. March 27-29, 2025
https://www.aaoallergy.org/education/aaoa-explorers-course-2025/

BackTable+ for ENT
https://plus.backtable.com/pages/ent

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Transcript Preview

[Dr. Jennifer Villwock]
Yes. We have a microbiome everywhere. Anywhere that basically our body is interacting with the outside world and even internally, there's an active microbiome there. I think for most people, the most common one that we hear about so much, and I think part of that is due to marketing of different supplements and other things, is the gut microbiome. I think a lot of our patients, especially our sinusitis patients are very well aware of the importance of the gut microbiome because they're treated with antibiotics, sometimes very routinely, and they experience all of those GI type symptoms, which sometimes can be worse or become chronic and overshadow some of the original reasons that they came to see us.

There's a skin microbiome. We're going to talk a little bit about the sinus microbiome.

The Materials available on BackTable are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.

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Topics

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