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2025 Genicular Nerve Ablation CPT Code

Bryant Schmitz • Updated Jun 30, 2025 • 37 hits
Genicular nerve ablation (CPT code 64624) is performed by pain management specialists, anesthesiologists, or orthopedic surgeons to treat chronic knee pain by ablating sensory nerves supplying the knee joint. This minimally invasive procedure often uses radiofrequency energy under imaging guidance to disrupt pain signals. This article clarifies appropriate use and billing of CPT code 64624.

Table of Contents
(1) CPT Code for Genicular Nerve Ablation
(2) Detailed Description of CPT Code 64624
(3) Coding & Billing Considerations
(4) Why Proper Coding Is Important
(5) What is a CPT Code?
(6) Disclaimer
CPT Code for Genicular Nerve Ablation
CPT code 64624 covers radiofrequency ablation of the genicular nerves for relief of chronic knee pain.
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Detailed Description of CPT Code 64624
CPT Code: 64624
• Code Description: Destruction by neurolytic agent, other peripheral nerve or branch (e.g., genicular nerve)
• Inclusions: Radiofrequency or chemical ablation of genicular nerves, imaging guidance (fluoroscopy or ultrasound), local anesthesia, multiple nerve branches treated in one session
• Exclusions: Diagnostic nerve blocks (use 64483–64484), neurostimulator placement, therapeutic injection procedures, follow-up visits, acupuncture or alternative therapies
Coding & Billing Considerations
• Append modifier 51 when multiple procedures are performed in the same operative session.
• Use modifier 59 to indicate that genicular nerve ablation is distinct from other procedures on the same date.
• Report laterality with modifier LT or RT according to the side treated.
• Ensure documentation of the number of nerve branches treated and imaging modality used.
• Do not report 64624 for diagnostic nerve block procedures.
• Confirm payer-specific requirements for prior authorization and documentation of conservative management failure.
Why Proper Coding Is Important
Accurate coding of CPT code 64624 ensures correct reimbursement and reduces claim denials by clearly distinguishing ablation therapy from diagnostic blocks or injection services. Proper code selection supports clinical documentation, treatment justification, and compliance with payer guidelines. This enhances patient records and aligns with pain management standards.
What is a CPT Code?
CPT stands for Current Procedural Terminology. These codes are used by medical professionals to describe procedures and services performed. CPT codes are crucial for the billing process, allowing healthcare providers to communicate with insurance companies and other payers about the procedures performed.
Disclaimer
The information provided here reflects our understanding of the procedure(s) and/or device(s). This information should not be construed as authoritative. We encourage you to consult CMS.
Podcast Contributors
Dr. John Smirniotopoulos
Dr. John Smirniotopoulos is an assistant professor of clinical radiology in the IR department at MedStar Georgetown University and MedStar Washington Hospital Center in DC.
Dr. Michael Barraza
Dr. Michael Barraza is a practicing interventional radiologist (and all around great guy) with Radiology Associates in Baton Rouge, LA.
Cite This Podcast
BackTable, LLC (Producer). (2023, July 19). Ep. 22 – Genicular Nerve Ablation [Audio podcast]. Retrieved from https://www.backtable.com
Disclaimer: The Materials available on BackTable.com are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.