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2025 Genicular Nerve Ablation CPT Code

Author Bryant Schmitz covers 2025 Genicular Nerve Ablation CPT Code on BackTable MSK

Bryant Schmitz • Updated Jun 30, 2025

Genicular nerve ablation (CPT code 64624) is performed by pain management specialists, anesthesiologists, or orthopedic surgeons to treat chronic knee pain by ablating sensory nerves supplying the knee joint. This minimally invasive procedure often uses radiofrequency energy under imaging guidance to disrupt pain signals. This article clarifies appropriate use and billing of CPT code 64624.

Table of Contents

CPT Code for Genicular Nerve Ablation

Detailed Description of CPT Code 64624

Coding & Billing Considerations

Why Proper Coding Is Important

What is a CPT Code?

Disclaimer

CPT Code for Genicular Nerve Ablation

CPT code 64624 covers radiofrequency ablation of the genicular nerves for relief of chronic knee pain.

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Genicular Nerve Ablation with Dr. John Smirniotopoulos, Dr. Michael Barraza on the BackTable MSK Podcast
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Episode # 22  •  19 Jul 2023

Genicular Nerve Ablation

In this episode, host Dr. Michael Barazza interviews Dr. John Smirniotopoulos about genicular nerve ablation, an innovative treatment option for the management of osteoarthritis.

Detailed Description of CPT Code 64624

CPT Code: 64624
• Code Description: Destruction by neurolytic agent, other peripheral nerve or branch (e.g., genicular nerve)
• Inclusions: Radiofrequency or chemical ablation of genicular nerves, imaging guidance (fluoroscopy or ultrasound), local anesthesia, multiple nerve branches treated in one session
• Exclusions: Diagnostic nerve blocks (use 64483–64484), neurostimulator placement, therapeutic injection procedures, follow-up visits, acupuncture or alternative therapies

Coding & Billing Considerations

• Append modifier 51 when multiple procedures are performed in the same operative session.
• Use modifier 59 to indicate that genicular nerve ablation is distinct from other procedures on the same date.
• Report laterality with modifier LT or RT according to the side treated.
• Ensure documentation of the number of nerve branches treated and imaging modality used.
• Do not report 64624 for diagnostic nerve block procedures.
• Confirm payer-specific requirements for prior authorization and documentation of conservative management failure.

Why Proper Coding Is Important

Accurate coding of CPT code 64624 ensures correct reimbursement and reduces claim denials by clearly distinguishing ablation therapy from diagnostic blocks or injection services. Proper code selection supports clinical documentation, treatment justification, and compliance with payer guidelines. This enhances patient records and aligns with pain management standards.

What is a CPT Code?

CPT stands for Current Procedural Terminology. These codes are used by medical professionals to describe procedures and services performed. CPT codes are crucial for the billing process, allowing healthcare providers to communicate with insurance companies and other payers about the procedures performed.

Disclaimer

The information provided here reflects our understanding of the procedure(s) and/or device(s). This information should not be construed as authoritative. We encourage you to consult CMS.

The Materials available on BackTable are provided for informational and educational purposes only and are not a substitute for the independent professional judgment of a qualified healthcare professional in diagnosing or treating patients. Any opinions, statements, or views expressed are those of the individual contributors and do not necessarily reflect those of the publisher, platform, or any affiliated organization.

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