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BackTable / OBGYN / Podcast / Episode #45

RhoGAM’s Role in Pregnancy: Facts & Controversies

with Dr. Matt Reeves

This episode of BackTable OBGYN features Dr. Matt Reeves, a seasoned OBGYN and CEO/Founder of the DuPont Clinic, and host Dr. Amy Park as they discuss the use of Rh immune globulin (RhoGAM) in pregnancy.

RhoGAM is traditionally administered to Rh- women at 28 weeks gestation, within 72 hours of birth, and frequently after an abortion in order to prevent Rhesus alloimmunization in future pregnancies. However, with recent data showing negligible Rh- blood cell exposure in early pregnancy terminations, the need for RhoGAM in such cases is being questioned. Additionally, considering the scarcity of RhoGAM and the reality of smaller family sizes globally, the importance of RhoGAM in Rh alloimmunization prevention might not be as significant as previously thought. However, limited evidence and ingrained medical practices may cause the transition to be slow.

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RhoGAM’s Role in Pregnancy: Facts & Controversies with Dr. Matt Reeves on the BackTable OBGYN Podcast)
Ep 45 RhoGAM’s Role in Pregnancy: Facts & Controversies with Dr. Matt Reeves
00:00 / 01:04

BackTable, LLC (Producer). (2024, January 23). Ep. 45 – RhoGAM’s Role in Pregnancy: Facts & Controversies [Audio podcast]. Retrieved from https://www.backtable.com

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Podcast Contributors

Dr. Matt Reeves discusses RhoGAM’s Role in Pregnancy: Facts & Controversies on the BackTable 45 Podcast

Dr. Matt Reeves

Dr. Matt Reeves is an obstetrician-gynecologist and the executive director of DuPont Clinic in the Washington DC area.

Dr. Amy Park discusses RhoGAM’s Role in Pregnancy: Facts & Controversies on the BackTable 45 Podcast

Dr. Amy Park

Dr. Amy Park is the Section Head of Female Pelvic Medicine & Reconstructive Surgery at the Cleveland Clinic, and a co-host of the BackTable OBGYN Podcast.

Show Notes

00:00 - Introduction
03:09 - Understanding RhoGAM: Origin and Development
06:06 - The Science Behind RhoGAM and Its Role in Pregnancy
08:13 - The Controversy and Debate Around RhoGAM Usage
11:52 - The Impact of RhoGAM on Public Health and Medical Practice
15:25 - The Future of RhoGAM: Perspectives and Predictions
29:24 - Closing Thoughts and Further Resources

Resources

Horvath, S., Goyal, V., Traxler, S., & Prager, S. (2022). Society of Family Planning committee consensus on Rh testing in early pregnancy. Contraception, 114, 1–5.
https://doi.org/10.1016/j.contraception.2022.07.002

Horvath S, Huang Z, Koelper NC, et al. Induced Abortion and the Risk of Rh Sensitization. JAMA. 2023;330(12):1167–1174. doi:10.1001/jama.2023.16953

Disclaimer: The Materials available on BackTable.com are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.

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