Dr. Cathy Eng
Medical Oncologist
1 Podcast on BackTable
Dr. Cathy Eng is a medical oncologist and the David H. Johnson Chair in Surgical and Medical Oncology at Vanderbilt University in Nashville, Tennessee.
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Episode # 75 • 04 Aug 2026
Applying CheckMate 8HW: Practical Updates for MSI-High CRC
with Dr. Cathy Eng, Dr. Jun Gong
Is it time to rethink the definition of “cure” for stage IV colorectal cancer? In this episode of BackTable Tumor Board, medical oncologist Jun Gong interviews Dr. Cathy Eng about updates from the phase III CheckMate-8HW trial in centrally confirmed MSI-high/dMMR metastatic colorectal cancer, comparing nivolumab/ipilimumab, nivolumab, and chemotherapy. They discuss initial findings demonstrating improved progression-free survival and response rates with combination immunotherapy, as well as safety considerations and how comorbidities and frailty guide the choice between single-agent and combination regimens.
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About
Cathy Eng, MD, FACP, FASCO, is a Professor of Medicine in the Division of Hematology and Oncology, Department of Medicine and is the co-director of GI Oncology and co-leader of the Gastrointestinal Cancer Research Program at Vanderbilt University Medical Center. She joined the faculty at Vanderbilt-Ingram Cancer Center in 2019.
Dr. Eng's primary research interests include clinical trials involving innovative drugs for the treatment of colorectal, anal and appendiceal cancers. She has a specific interest in early onset colorectal cancer patients and has published extensively on these GI malignancies.
Nationally, Dr. Eng has served in multiple leadership roles for ASCO, ASCO GI, ECOG, SWOG and the National Cancer Institute (NCI). She is currently serving as the VICC SWOG lead investigator and is the co-chair for the NCI Gastrointestinal Steering Committee.
Visit Vanderbilt Health to learn more about Dr. Cathy Eng.
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