Topic
Brain Metastasis
1 Podcast on BackTable
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Episode # 48 • 17 Feb 2026
HER2-Positive Metastatic Breast Cancer: Treatment Insights & Protocols
In a patient with metastatic HER2-positive breast cancer, what should guide the next decision: trial data, toxicity, or durability of response? In this episode of BackTable Tumor Board, Dr. Lindsay Peterson (Washington University) sits down with Dr. Erica Hamilton (Sarah Cannon Research Institute) to examine how next-generation HER2-directed therapies are reshaping the management of metastatic disease. As treatment options expand beyond trastuzumab-based regimens to agents such as trastuzumab deruxtecan and tucatinib, clinical decision-making increasingly hinges on sequencing strategy, interpretation of evolving trial data, and thoughtful toxicity management.
More on Brain Metastasis
Tumor Board Episode #48
Feb 17, 2026
with Dr. Erika Hamilton, Dr. Lindsay Peterson
In a patient with metastatic HER2-positive breast cancer, what should guide the next decision: trial data, toxicity, or...
180+ listens
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