.png){kind=small}
.png){kind=small}
BackTable / Urology / Podcast / Episode #274
Techniques & Challenges in Bladder Transplant Surgery
with Dr. Nima Nassiri
For the first time in history, a human bladder was transplanted. Dr. Nima Nassiri (UCLA) joins Dr. Ruchika Talwar to share how his team completed this landmark operation alongside a kidney transplant. He walks through the clinical scenario, key steps in donor and recipient selection, and how years of preclinical work informed the operative approach.
Be part of the conversation. Put your sponsored messaging on this episode. Learn how.
BackTable, LLC (Producer). (2025, November 18). Ep. 274 – Techniques & Challenges in Bladder Transplant Surgery [Audio podcast]. Retrieved from https://www.backtable.com
Stay Up To Date
Follow:
Subscribe:
Sign Up:
Podcast Contributors
Synopsis
The conversation explores the broader future of bladder transplant surgery, from ethical considerations to the potential for merging bladder transplantation with tolerance-induction protocols that could one day eliminate the need for lifelong immunosuppression. Dr. Nassiri reflects on the importance of patient-first decision-making, teamwork, and careful innovation as the field moves toward new possibilities in restorative urology and transplant medicine.
Timestamps
00:00 - Introduction
02:51 - The Path to Bladder Transplant Surgery
05:00 - Scientific Challenges and Barriers
06:45 - Patient Selection and Initial Outcomes
12:28 - Quality of Life Considerations
14:18 - Performing the First Bladder Transplant
18:59 - Donor Matching
21:28 - Ethical Considerations
24:51 - Research Gaps and Future Prospects
Resources
Clinical Trial: Vascularized Composite Bladder Allograft Transplantation
https://www.clinicaltrials.gov/study/NCT05462561
Clinical Trial: Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney Transplants
https://clinicaltrials.gov/study/NCT05525507
The Materials available on BackTable are provided for informational and educational purposes only and are not a substitute for the independent professional judgment of a qualified healthcare professional in diagnosing or treating patients. Any opinions, statements, or views expressed are those of the individual contributors and do not necessarily reflect those of the publisher, platform, or any affiliated organization.
Up Next
Articles
Topics
