Episode # 16 • 09 Dec 2025
The Evolution of TAVR: Historical Insights & Future Innovations
Transcatheter aortic valve replacement (TAVR) may be a standard cardiac procedure today, but its origin story follows an intriguing tale of courage, innovation and heart. In this episode of BackTable Cardiology, renowned cardiothoracic surgeon Dr. Michael Mack, a global leader in structural heart disease from Baylor Scott White Health, shares the history of TAVR, highlighting its origins, key clinical trials, and the eventual success of TAVR as a primary therapy.
Timestamps
00:00 - Introduction
02:27 - Inception of TAVR
03:01 - The Global Reach of TAVR
11:10 - Placement of Aortic Transcatheter Valves (PARTNER) Trial
19:10 - Advancements in Cardiac Imaging
20:35 - Mapping the Next Five Years
23:20 - Strides in Aortic Insufficiency
25:16 - Collegiality in Cardiac Care
Resources
- How Transcatheter Aortic Valve Implantation (TAVI) Was Born: The Struggle for a New Invention
- Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
- Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years
- Dr. Michael Mack Provider Profiles
- Dr. Sameh Sayfo Provider Profile
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More about this episode
Dr. Michael Mack and host Dr. Sameh Sayfo discuss the early adaptations, challenges, and adoption of TAVR, detailing the collaborative efforts amongst medical professionals that led to its widespread utilization. They also explore the future of valve technology and the importance of multidisciplinary teamwork in advancing cardiovascular care. The discussion concludes with insights into emerging heart technologies and the evolving partnership between different medical specialties.
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