Episode # 133 • 08 Sept 2026
Advances in Endometriosis: Diagnosis & Management
Advances in endometriosis research are reshaping how clinicians diagnose, understand, and treat this complex multisystem condition. On this episode of BackTable Women’s Health, Dr. Nicole Faulkner welcomes Dr. Hugh Taylor for an in-depth discussion of the systemic nature of endometriosis, including its metabolic, psychological, and cardiovascular effects, as well as central pain sensitization and bowel and bladder symptoms. They also explore how animal models and biomarkers like microRNAs are deepening our understanding of these connections.
Timestamps
00:00 - Introduction
03:26 - Endometriosis Beyond the Pelvis
05:17 - Understanding Systemic Symptoms
10:35 - Why Diagnosis Takes Years
12:54 - Key Clues to Endometriosis
14:35 - Emerging Noninvasive Diagnostics
18:13 - Pain Versus Disease Stage
19:33 - Precision Medicine Approaches
24:04 - Treatment Strategies and Follow-Up
27:17 - GnRH Antagonists and Add-Back Therapy
29:45 - Danazol and Surgical Options
34:26 - Future of Immune-Based Therapies
37:49 - Fertility Counseling and Egg Freezing
40:17 - Wrap-Up and Key Takeaways
Resources
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More about this episode
Given that many patients wait years for a diagnosis, Dr. Taylor emphasizes the importance of presumptive clinical diagnosis and selective imaging to expedite treatment. He highlights emerging biomarkers that may offer more noninvasive diagnostic options and help clarify pain mechanisms. The conversation reviews current management strategies, including continuous oral contraceptives, the challenge of progestin resistance, and the promise of blood-based tests to predict treatment response. They also discuss GnRH antagonists, Danazol, surgery for refractory cases, and future directions such as immune-based therapies targeting the inflammation and immune dysfunction at the root of endometriosis.
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