

Episode # 639 • 30 Apr 2026
Advancements in Ablation Techniques for Liver Tumors
Why settle for “good enough” ablation margins when today’s tools can deliver more and decrease the risk of recurrence? Host Dr. Kavi Krishnasamy sits down with interventional radiologists Dr. Christopher Malone (WashU, St. Louis) and Dr. Kirema Garcia-Reyes (Mount Sinai, NYC) at our 2026 HCC Creator Weekend™ in-studio in New Orleans to discuss modern liver ablation strategies for HCC and metastatic disease. The conversation centers on challenging real-world cases, combining multidisciplinary tumor board insights with hands-on experience using ablation confirmation software, radiofrequency, cryo, and microwave ablation.
Timestamps
00:00 - Introduction
01:55 - Challenging HCC Case
03:42 - Ablating by Anatomy Alone?
06:25 - Where Ablation Fits
10:35 - SURF Trial Takeaways
15:09 - Central Cryo Safety Debate
16:30 - HCC Case Setup and Mapping
21:27 - Ablation Confirmation Workflow
24:03 - HEPA Catheter Cone Beam Approach
25:38 - Follow Up Imaging Cadence
27:38 - Final Thoughts and Anticipating What is to Come
Resources
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More about this episode
The doctors emphasize that ablation outcomes hinge on achieving adequate margins and argue that “ablating by anatomy” without lesion visualization is increasingly unjustifiable, highlighting data showing ablation confirmation software improves margins and reduces local recurrence despite a learning curve and registration challenges. They review patient selection by size and location, when to favor radiation segmentectomy versus percutaneous ablation, and central lesion cautions near the hilum or bile ducts. A cryoablation case illustrates pivoting when Y90 mapping fails, and covers cryo advantages and limitations. They also cover follow-up imaging cadence and stress clinician-level longitudinal care and referral communication.
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