Episode # 256 • 22 Aug 2025
The Role of ctDNA in Bladder Cancer Diagnosis & Treatment
Could ctDNA testing allow us to treat bladder cancer earlier, smarter, and more effectively? In this episode of BackTable Urology, Dr. Alberto Pieretti, a urologic oncologist at Cleveland Clinic Weston Hospital, joins host Dr. Jose Silva to explore the emerging role of ctDNA in bladder cancer management.
Timestamps
00:00 - Introduction
02:50 - Overview of Bladder Cancer
12:59 - Overview of ctDNA
20:34 - Current ctDNA Trials
27:21 - Clinical Implications of ctDNA
31:20 - Conclusion
Resources
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More about this episode
Dr. Pieretti and Dr. Silva discuss how ctDNA can refine staging, identify patients at risk of recurrence, and guide decisions on when to intensify treatment. The conversation also examines its potential to detect actionable mutations, inform precision therapies, and shape the design of future clinical trials in urologic oncology.
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