Dr. Sam Chang
Urologic Oncologist
2 Podcasts on BackTable
Dr. Sam Chang is the chief of urologic oncology at Vanderbilt University in Nashville, Tennessee.
Learn from the experiences and expertise of Dr. Sam Chang and other leading voices in your specialty on the BackTable app.
Episode # 305 • 02 Jun 2026
Immune Therapy Innovations for BCG Unresponsive Cancer
Ready to move beyond “one-size-fits-all” for BCG-unresponsive NMIBC? In this episode of BackTable Urology, Dr. Ruchika Talwar hosts Dr. Sam Chang to discuss the evolving treatment landscape for BCG-unresponsive non-muscle invasive bladder cancer (NMIBC). They explore why BCG may fail, the science and clinical rationale behind new immunotherapies and gene therapies, practical approaches to patient selection, treatment sequencing, and surveillance, and the value of emerging biomarkers, empowering urologists to make more informed, personalized decisions in complex cases of NMIBC.
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About
Dr. Sam Chang is the Chief Surgical Officer at the Vanderbilt Ingram Cancer Center and the Urologic Oncology Division Chief. He received his medical degree from Vanderbilt and also completed his residency at Vanderbilt. After this continued his medical training with a fellowship at Memorial Sloan-Kettering Cancer Center.
Dr. Chang formerly chaired the American Joint Committee on GU Cancer Staging and the AUA/ASCO Guidelines on Bladder Cancer and was a member of the AUA Guidelines on Renal Cancer and the SUO Guidelines on Advanced Prostate Cancer. He is the past Chair of the American Board of Urology Examination Committee responsible for U.S. board certification and has been selected to serve as a Trustee of the American Board of Urology. His research in urologic oncology and clinical efforts have been recognized with national awards include the Distinguished Service Award of the SUO and the Gold Cystoscope Award and Hugh Hampton Young Award from the AUA.
Visit Vanderbilt University Medical Center to learn more about Dr. Sam Chang.
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