

Episode # 169 • 28 May 2024
Prostate Cancer: Navigating Focal Therapy Options
In this episode, Dr. Matthew Cooperberg (UC San Francisco) and Dr. Arvin George (Johns Hopkins) join host Dr. Aditya Bagrodia in a conversation about guidelines and treatment algorithms for focal therapy in prostate cancer treatment.
Timestamps
00:00 - Introduction
05:24 - Focal Therapy Definitions, Techniques, and Patient Selection
11:45 - Ideal Patients for Focal Therapy
25:30 - The Role of Genomic Classifiers in Treatment Decisions
30:56 - Addressing High-Risk Patient Concerns
37:51 - Advancements and Considerations in Focal Therapy Modalities
56:13 - The Future of Focal Therapy
Resources
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More about this episode
First, the doctors discuss focal therapy in prostate cancer treatment from various perspectives, including the challenges of treating certain lesions, the comparison of different focal therapy modalities like high-intensity focused ultrasound (HIFU) and brachytherapy, cryotherapy and the importance of patient-specific factors in treatment decisions. They emphasize the need for clinical trials and registries to validate focal therapy outcomes, the potential expansion of indications for focal therapy, and the critical role of advanced imaging and genomic classifiers in patient selection and treatment planning. The discussion also touches on the potential of focal therapy to evolve as a standard care option alongside advancements in understanding the biology of prostate cancer and improving imaging and treatment technologies.
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