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BackTable / Urology / Podcast / Episode #240
Erectile Dysfunction Therapies: Testosterone, PD-5 Inhibitors, and Beyond
with Dr. Mohit Khera
Can we do more than prescribe pills to address men’s sexual health complaints? In this episode of the BackTable Urology Podcast, men’s health expert Dr. Mohit Khera from Baylor College of Medicine joins guest host Dr. Amy Pearlman for a deep dive into testosterone management and the full spectrum of erectile dysfunction therapies.
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BackTable, LLC (Producer). (2025, June 13). Ep. 240 – Erectile Dysfunction Therapies: Testosterone, PD-5 Inhibitors, and Beyond [Audio podcast]. Retrieved from https://www.backtable.com
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Synopsis
The conversation covers daily tadalafil use, lifestyle optimization, and the nuanced role of off-label medications. Dr. Khera also highlights emerging technologies like the Tech Ring and radiofrequency treatments, alongside practical insights into semen analysis and hormonal health markers. Throughout, he emphasizes a holistic, patient-centered approach to sexual health—blending medical therapy with meaningful lifestyle change. This is a must-listen for general urologists, men’s health specialists, and trainees looking to expand their toolkit in this evolving field.
Timestamps
00:00 - Introduction
02:13 - Erectile Dysfunction and Testosterone
08:05 - Young Men's Health and Early Detection
10:20 - Semen Analysis for Overall Health
12:50 - Daily Tadalafil and Its Benefits
16:40 - Proactive Sexual Health Management
21:28 - Female Sexual Health
25:16 - Treating Delayed Ejaculation
28:53 - Psychogenic Erectile Dysfunction
31:16 - Technology in Sexual Health
35:54 - Lifestyle Modifications for Better Sexual Health
41:55 - Resources and Referrals for Patients
44:30 - Final Thoughts
Transcript Preview
That's what we do for sexual medicine. We wait for the ED, and then we treat it. Then the ED gets worse because our treatment is just a band-aid on a problem. Then we go to the injection and the implant. Wouldn't it be great if you met the patient 20 years earlier somehow, before they had the ED, and we started something that would prevent the ED from happening in the first place? That would be ideal. It's idealistic. Maybe that can't happen. I do look at the patient presenting with mild ED who asked for Viagra as exactly the patient who presents, who gets a hemoglobin A1c, and it's 5.9. He's pre-diabetic. He's sitting there. You have a couple of options.
Now, you can start with lifestyle modification of that pre-diabetic and get that hemoglobin A1c below 5.7, and the same goes for that guy you're giving Viagra to. You can either help him now and help him reduce the ED with lifestyle modification, which does work, or you just let the ED and the diabetes get worse, and you treat it when it goes on. That's what we do right now. We just give them the Viagra and say, "Call me when it stops working." You start the injections, "Call me when it stops working. Okay, let's go to the implant." That's our model. That's the model we do today. It's very archaic.
The Materials available on BackTable are for informational and educational purposes only and are not a substitute for the professional judgment of a healthcare professional in diagnosing and treating patients. The opinions expressed by participants of the BackTable Podcast belong solely to the participants, and do not necessarily reflect the views of BackTable.
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