Episode # 409 • 24 Jan 2024
Thrombectomy for Large Core Infarctions: Balancing Benefits & Risks
In this episode of the BackTable Podcast, guest host Dr. Krishna Amuluru interviews Dr. Fawaz Al-Mufti about recent trials on large core strokes and how they may impact practice. Dr. Al-Mufti is a practicing neurointerventionalist and serves as the Associate Chair of Neurology for Research at New York Medical College.
This podcast is supported by
Timestamps
00:00 - Introduction
02:53 - Large Ischemic Core Infarcts
06:06 - The Importance of ASPECTS
11:59 - Large Ischemic Core Trials
23:37 - Socioeconomic Implications of Thrombectomy
38:08 - The Future of Thrombectomy
Resources
- Mission Thrombectomy
- The Alberta Stroke Program Early CT score (ASPECTS): A predictor of mortality in acute ischemic stroke
- Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomized trials (HERMES Study)
- Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging (DEFUSE III Trial)
- Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct (DAWN Trial)
- Endovascular Therapy for Acute Stroke with a Large Ischemic Region (RESCUE-Japan Trial)
- Trial of Endovascular Thrombectomy for Large Ischemic Strokes (SELECT2 Trial)
- TESLA Trial: Rationale, Protocol, and Design
- Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomized trial (TENSION Trial)
- Evaluation of acute mechanical revascularization in large stroke (ASPECTS ⩽5) and large vessel occlusion within 7 h of last-seen-well: The LASTE multicenter, randomized, clinical trial protocol
- Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct (ANGEL-ASPECT Trial)
- Acute endovascular stroke therapy (Dr. Mike Chen Review)
- Mechanical thrombectomy is cost-effective versus medical management alone around Europe in patients with low ASPECTS (European Cost Effectiveness Study)
- Mechanical Thrombectomy Global Access For Stroke (MT-GLASS): A Mission Thrombectomy (MT-2020 Plus) Study
- Noncontrast Computed Tomography vs Computed Tomography Perfusion or Magnetic Resonance Imaging Selection in Late Presentation of Stroke With Large-Vessel Occlusion
You may also like
More about this episode
Dr. Al-Mufti examines the cost-effectiveness and socioeconomic implications of successful treatment of patients with large core strokes. The doctors highlight various stroke thrombectomy trials including the RESCUE-Japan, SELECT2 Trial, and TENSION trials. The discussion also covers how these findings affect thrombectomy expansion in lower resource settings and the future outlook of endovascular thrombectomy procedures.
The Materials available on BackTable are provided for informational and educational purposes only and are not a substitute for the independent professional judgment of a qualified healthcare professional in diagnosing or treating patients. Any opinions, statements, or views expressed are those of the individual contributors and do not necessarily reflect those of the publisher, platform, or any affiliated organization.