Dr. Neil Desai

Neil Desai, M.D., M.H.S., is an Associate Professor and Director of Clinical Research in the Department of Radiation Oncology at UT Southwestern Medical Center. Dr. Desai earned his medical degree at Yale University, where he also conducted cancer biology research that led to a master’s degree. He completed residency training in radiation oncology at Memorial Sloan Kettering Cancer Center in New York.
Dr. Desai considers it a privilege to treat patients with cancer. He says he remains inspired by his physician-scientist mentors, who demonstrated not only the great potential of bringing advances to the clinic but also the humbling need to keep a patient’s goals and values in highest focus. Dr. Desai does both as a specialist in genitourinary and hematologic malignancies and as an expert who strives to match the ideal treatment to each patient’s disease.
Between his time at Dartmouth College and Yale University School of Medicine, Dr. Desai participated in research to help determine which patients would benefit from a new class of targeted cancer drugs, and he helped develop new technologies for detecting the genetic alterations that determine a tumor’s aggressiveness.
During his residency training at Memorial Sloan Kettering Cancer Center in New York, he investigated how to apply specific treatments – including radiotherapy – to patients by considering factors such as disease biology and risk. His work culminated in the nationally recognized laboratory of David Solit, M.D., under whom he examined the impact of genetic alterations in the DNA damage response on the success of bladder-preserving chemoradiation for bladder cancer.
At UT Southwestern, Dr. Desai is committed to developing and participating in clinical trials designed to improve treatments for patients with genitourinary and hematologic cancers. He has a particular interest in prostate and bladder cancers, for which he notes that the need to improve treatment selection for a patient is as important as increasing treatment efficacy